Table 6.

Prevalence of aging-related phenotypes in relation to FOXO3A3 genotype

FOXO3A3 Genotype
TTTGGGP
CHD prevalence, %
    Average-lived32.318.323.10.010
    Long-lived7.47.67.70.998
    All25.714.015.40.002
Stroke prevalence, %
    Average-lived6.78.57.70.813
    Long-lived4.91.93.80.510
    All6.35.85.80.974
Cancer prevalence, %
    Average-lived22.418.311.50.326
    Long-lived17.312.47.70.400
    All21.115.99.60.075
Diabetes prevalence, %
    Average-Lived60.662.350.00.498
    Long-Lived57.564.150.00.368
    All59.863.050.00.212
  • P values based on χ2 test comparing frequency of GG genotype to other genotypes for average lived controls (n = 402), long lived cases (n = 213), and all subjects (n = 615).