Table 1.

Digital RMD and fetal genotype classification of CD41/42 (–CTTT)

CasesNo. of panels*Fetal genotypeM countN countBoth positiveNet MNet NActual fetal %§Reference allelemrSPRT**
M6224NN4245171441050310.7M0.02NN
M6612NN201264719425710.7M0.02NN
M7412MN3938423036381210.0M0.04NN
M9312NN269344826133615.3M0.03NN
M9924MN709696216886756.2N0.04U
  • M, mutant allele; N, wild-type allele.

  • *Each panel consists of 765 wells.

  • Wells positive for both alleles.

  • Wells only positive for the mutant allele and not wild-type allele or vice versa.

  • §Determined by the digital ZFY/X assay.

  • Reference allele is the one with the lesser count in each sample.

  • Template concentration of the reference allele.

  • **U, unclassified; bold font, misclassified.