Table 1.

IP6K1 knockout male mice are sterile, whereas females are fertile*

Genotype
Rate of pregnancyLitter size
MaleFemale
−/−+/+0/50
−/−−/−0/50
+/−+/+4/58.8 ± 1
+/−−/−4/57.8 ± 0.9
+/−+/−7/128.5 ± 1
  • *Three-month-old males and females of the specified genotype were paired for 7 days. The number of pregnant females and the number of pups in each litter were counted. Litter sizes are expressed as mean ± SE for each female.