Table 1.

Expression of consensus HESC signature genes in human iPS clones

Table 1.
  • iPS clones express most of the HESC signature genes. Genes that are consistently highly expressed between many available HESC lines as determined by the indicated references were analyzed for their expression levels in iPS clones and early OCT4/C-MYC clones 54 and 100 by using microarray data. Note that most HESC genes are induced (denoted with I) in properly reprogrammed iPS clones (2 and 5), whereas these genes in OCT4/C-MYC clones and control cells are often not changed (NC). As determined by GCOS array analysis software: I, increased relative to NHDF; NC, no change relative to NHDF; P, present call; A, absent call; M, marginal call. a, up-regulated in ref. 12; b, up-regulated in ref. 13; c, up-regulated by International Stem Cell Consortium (14); d, defined factors to induce pluripotency; fold is Log2.