Table 1.

Complete blood count of AEP-deficient mice at the age of 6 months

Parameter+/− (n = 8)−/− (n = 8)
Body weight, g30.9 ± 3.128.2 ± 3.7
Spleen weight, mg153 ± 45330 ± 142
RBCs, 104/μL971 ± 50798 ± 120
Hemoglobin, g/dL13.8 ± 0.610.9 ± 1.6
Hematocrit, %47.2 ± 1.838.2 ± 5.1
Mean corpuscular volume, fL48.6 ± 1.248.0 ± 1.0
Mean corpuscular hemoglobin, pg14.2 ± 0.413.7 ± 0.3*
Mean corpuscular hemoglobin conc., g/dL29.2 ± 0.428.7 ± 0.5*
Total WBCs, 102/μL36.5 ± 13.836.1 ± 9.7
    Lymphocytes, 102/μL23.6 ± 13.221.3 ± 5.6
    Monocytes, 102/μL6.0 ± 2.29.1 ± 5.3
    Neutrophils, 102/μL6.6 ± 5.35.5 ± 1.8
Platelets, 104/μL79.8 ± 16.558.2 ± 33.4
  • Data are expressed as mean ± SD.

  • *, P < 0.05;

  • †, P < 0.01;

  • ‡, P < 0.005; Student's t test, n = 8.