Table 1.

Kds for the homodimerization of N-cadherin and E-cadherin EC1–2 proteins from mouse, human, and chicken

SpeciesKd 25 °C, μM
Kd 37 °C, μM
N-cadherinE-cadherinCadherin-6N-cadherinE-cadherin
Mouse25.8 ± 1.596.5 ± 10.63.13 ± 0.1222.6 ± 1.7160.0 ± 21.3
Human24.6 ± 5.0156.0 ± 10.0NA*22.1 ± 6.5217 ± 30
Chicken19.7 ± 2.062.0 ± 9.5NA*20.4 ± 1.4110.0 ± 6.8
  • *Binding of cadherin-6 was tested only for mouse.