Table 3.

Analysis of the effect of fibroblasts on the expression of NKp44 and correlation with the ability to release PGE2

Fibroblast cell lines% NKp44 m.f.i. inhibition (Fibr/NS398)*PGE2 (pg/ml) without NKPGE2 (pg/ml) with NK
Patient #1TF169/484,294.66,916
Patient #2TF284/591,8024,617
Patient #3TF362/n.d.1,5806,810
Patient #4TF495/06,6166,650
Patient #5TF571/n.d.n.d.n.d.
Patient #6TF671/702961,302
Patient #7TF755/18557.31,033.3
Patient #8TF861/03446,092
Patient #9TF958/n.d.6,7106,812
Patient #10TF1092/443,041.36,622
Patient #11TF1172/554,67715,107
Healthy #1HF1025.441.4
Healthy #2HF2029.2394.7
Healthy #3CRL-21069/237.788.7
Healthy #4CRL-220141/38212.2231.2
  • *values indicate the % of NKp44 m.f.i. inhibition induced by fibroblasts either in the absence or in the presence of PGE2 inhibitor NS398.