Table 2.

Glycolytic dependency induced by treatment with rapamycin

Rapamycin (nM)2DG (mM)CI
51.50.46
520.071
52.50.006
559.51E-05
201.50.317
2020.166
202.50.038
2052.53E-05
401.50.056
4020.181
402.50.112
4050
  • The synergy of glycolytic inhibitor 2-deoxyglucose with rapamycin was measured by calculating the CI of various cotreatments. A CI < 1 indicates synergy.