Table 1.

Polyp number and age of death for transgenic mice

Average no. polyps per mouse
Group*Number per groupLarge intestineSmall intestineTotalDate of death
Test3814.734536085
Control 1574.2178182110
Control 292.4113115120+
Control 31002110112120+
  • *Groups: Test = ApcMin × Rosa26-LsL-SB11 × T2/Onc × Vil-Cre; Control 1 = littermates harboring either ApcMin × Rosa26-LsL-SB11 or ApcMin × Rosa26-LsL-SB11 × T2/Onc or ApcMin × Rosa26-LsL-SB11 × Vil-Cre; Control 2 = littermates harboring either ApcMin × T2/Onc or ApcMin × Vil-Cre or ApcMin × T2/Onc × Vil-Cre; Control 3 = contemporaneous mice harboring ApcMin only.

  • Average number of polyps per mouse by large intestine, small intestine, and total.

  • Control groups 2 and 3 were killed at 120 d whether they were moribund or not.