Table 5.

Effect of MNR on regulatory key proteins

Protein expression (area of IR, mm2 × 10−2)ControlsMNR
AChE
 SVZ6.52 ± 2.045.07 ± 3.00
 Intermediate zone2.76 ± 0.692.45 ± 0.79
 Cortical plate6.16 ± 2.206.83 ± 2.44
β-Actin
 SVZ9.95 ± 4.069.94 ± 2.50
 Intermediate zone1.89 ± 0.871.61 ± 0.45
 Cortical plate13.89 ± 4.098.29 ± 2.59*
EphB2
 SVZ0.60 ± 0.170.85 ± 0.32
 Intermediate zone1.15 ± 0.580.88 ± 0.57
 Cortical plate5.13 ± 1.672.84 ± 0.66*
MHC-B
 SVZ13.32 ± 2.809.18 ± 2.32*
 Intermediate zone6.76 ± 2.537.89 ± 1.47
 Cortical plate8.42 ± 1.887.60 ± 1.63
PSA-NCAM
 SVZ6.28 ± 2.755.85 ± 1.53
 Intermediate zone4.38 ± 0.842.61 ± 0.70*
 Cortical plate6.14 ± 1.884.59 ± 1.51
ZPR1
 SVZ9.26 ± 5.746.78 ± 1.35
 Intermediate zone6.01 ± 1.796.11 ± 1.40
 Cortical plate13.28 ± 2.0613.01 ± 2.31
Bcl-2 (optical density, arbitrary units)
 SVZ53.92 ± 14.2785.48 ± 13.97**
 Intermediate zone41.50 ± 11.4462.28 ± 10.84*
 Cortical plate65.08 ± 19.1993.24 ± 12.10*
  • *P < 0.05; **P < 0.01 in comparison to controls.