Table 2.

IRF Expression in Bb-stimulated human monocytes

n = 6No inhibitorTLR8-inhibited
IRF 3−1.1 ± 0.5*−2.1 ± 0.1
IRF 50.03 ± 0.6*−2.2 ± 0.3
IRF 77.2 ± 1.3*1.6 ± 0.1
  • Values represent relative changes in gene expression compared with GAPDH.

  • *P < 0.05 (Mann–Whitney U test). Comparison analysis between inhibited and uninhibited Bb-stimulated human monocytes.