Table 1

Anatomical localization of the β-gal-stained cells in transgenic mice constructed with wild-typed (WT) 1,163-bp promoter of the nAChR β2-subunit gene and T1–T10 (same length of promoter point mutated in NRSE).

StructuresWTT1T2T3T4T5T6T7T8T9T10
Cortex±+++±±±±+
Superior colliculus+±++++++++
Thalamus+±
Mesencephalon+
Hypothalamus±
Basal telencephalon ±±
Spinal cord±±
Brain stem+±±+
Otic ganglion+
Eighth ganglion++++
Superior cervical ganglion+±
Dorsal root ganglion+±
Trigeminal ganglion±±
Cartilage (vertebra)±+
Mouth mucosa+++
  • Mice T9 and T10 have stably integrated the transgene. —, no staining.