Table 2

SaI/Ak, but not SaI/Ak/Ii or SaI/CIITA, tumor cells present peptides derived from ER-retained‚ÄČlysozyme

APC (erHEL-transfected)IL-2, pg/ml
Exp. 1Exp. 2Exp. 3Exp. 4Exp. 5Exp. 6
SaI or SaI/LXSN000
SaI/Ak79.247.585.859419899
SaI/Ak/Ii-7009.9
SaI/Ak/Ii-9000
SaI/CIITA000
  • APC are transfectants expressing approximately equivalent levels of erHEL (see flow cytometry profiles in Fig. 1). APC were cocultured with 3A9 hybridoma cells, and IL-2 release was measured by ELISA. Six independent experiments are shown.¬†