Table 2

Levels of allelic polymorphism recorded in genes of pathogenic bacteria

OrganismNo. of genes or gene segmentsDs*Relative variation
M. tuberculosis complex26<0.011
Shigella sonnei 20.011
Vibrio cholerae 10.4141
Streptococcus pyogenes 31.02102
Neisseria meningitidis 46.18618
M. avium-intracellulare 110.101,010
Escherichia coli 1111.771,177
Borrelia burgdorferi 3≈20≈2,000
Salmonella enterica 542.084,208
  • * Average number of synonymous substitutions per 100 synonymous sites (28), calculated on the basis of sequence information published elsewhere (12-27). The value reported for S. sonnei includes both synonymous and nonsynonymous sites and is based on RFLP analysis (15). 

  • Calculated relative to the Ds value of the M. tuberculosis complex. 

  • Includes some unpublished data.