Table 1

Distribution of pure and mixed adenomas within the intestines of ROSA26/+ ApcMin/+ ↔ +/+ ApcMin/+ chimeras

ChimeraIntestinal regionNumber of intestinal adenomas
Mixed blue/whitePure bluePure whiteTotal
112PSI0099
MSI212427
DSI445361
LI1078
Total7593105
113PSI312428
MSI405559
DSI606066
LI2002
Total151139155
  • The numbers of pure blue and mixed adenomas were determined from detailed serial section analysis. The composition of each of a sample of 10 overtly pure white adenomas was assessed by analysis of serial sections, whereas the remaining pure white adenomas were scored from whole-mount analysis only. For both chimeric mice the entire small and large intestines were scored. LI, large intestine; PSI, proximal small intestine; MSI, middle small intestine; DSI, distal small intestine.