Characterization of representative tumors from HGF/SF transgenic mice

Tumor no.Age, monthsTG lineSexHistological classificationTissue of origin
11037MAmelanotic melanoma*Skin
41222FAdenocarcinomaMammary
331322FHair follicle tumorSkin
381622MRhabdomyosarcomaSkin
391822FAdenosquamous carcinomaMammary
401222FAdenosquamous carcinomaMammary
411737MAmelanotic melanomaExorbital
472031MHemangiosarcomaLiver
62519FFibrosarcomaSkin
70437MRhabdomyosarcomaSkin
791522FAdenocarcinomaMammary
821418MFibrosarcomaSkin
911422MAdenocarcinomaSalivary
931737MHepatocellular adenomaLiver
951137MAmelanotic melanomaSkin
991427FAdenocarcinomaMammary
  • Description of tumors (identified by number) arising in HGF/SF transgenic (TG) mouse lines subjected to molecular and biochemical analyses shown in Fig. 2. In addition to the tumor types listed above, the following were detected in one or more HGF/SF transgenic mice: adrenal cortical adenoma, basal cell tumor, clitoral gland adenoma, harderian gland adenoma, hemangioma, hepatocellular carcinoma, histiocytic sarcoma, metastatic lymphoblastic lymphoma, olfactory gland adenocarcinoma, squamous cell papilloma, and thyroid follicular cell adenoma. M, male; F, female. 

  • Malignant with metastases.