Table 1

Use of nonhuman primate CXCR4 and CCR5 homologs by SIV

SIVmac251SIVmac239SIVmac316SIVmac316mutSIVB670-Cl3SIVmac17E-FrHIV-1 BH8
Human CXCR4+++
Rhesus CXCR4+/−+++
Human CCR5++++++++++++++++++
Rhesus CCR5++++++++++++++++
Pigtail CCR5++++++++++++++++++
Cynomologous CCR5+++++++++++++
Chimpanzee CCR5++++++++++++++++
Gorilla CCR5++++++++++++++++
Baboon CCR5+++++++++++++++++
  • Symbols correspond to signal-to-noise ratios (S:N) of: −, S:N ≤ 5; +/−, 5 < S:N ≤ 10; +, 10 < S:N ≤ 20; ++, 20 < S:N ≤ 50; +++, S:N > 50.