Table 2

Rate and equilibrium constants for kinetic models of actin nucleation by Arp2/3 complex

MonomerDimerTrimer
k+127.7 μM−1s−11.22 μM−1s−1371 μM−1s−1
k−1290 s−10.002 s−110−5 s−1
K d1 10.4 μM0.0016 μM2.7 × 10−8 μM
k+26.4 μM−1s−1
k−2650 s−1
K d2 101 μM
kf4.2 × 10−5 s−13.91 × 10−5 s−18.0 × 10−4 s−1