Table 1

Competition of disruption strains against wild type

StrainsRnP
TD84*0.228  ±  0.0460.9925<0.001
TD24*0.220  ±  0.0610.9924<0.001
TD880.216  ±  0.1570.8705<0.05
TD83*0.215  ±  0.0750.9775<0.001
TD30*0.159  ±  0.0220.9944<0.001
TD870.104  ±  0.0250.9944<0.001
TD66*0.098  ±  0.0180.9935<0.001
TD920.094  ±  0.0140.9965<0.001
TD100.090  ±  0.0180.9886<0.001
TD370.058  ±  0.0080.9927<0.001
TD610.045  ±  0.0100.9817<0.001
TD640.045  ±  0.0070.9936<0.001
TD20.013  ±  0.0030.9388<0.001
TD80.013  ±  0.0040.92812<0.001
TD190.012  ±  0.0010.9969<0.001
TD230.011  ±  0.0030.9238<0.01
TD480.010  ±  0.0030.9825<0.001
TD270.006  ±  0.0030.9227<0.01
TD790.006  ±  0.0040.8896<0.01
TD520.006  ±  0.0040.8477<0.01
TD210.005  ±  0.0010.9688<0.001
TD800.005  ±  0.0030.8717<0.01
TD630.004  ±  0.0010.97210<0.001
TD40.003  ±  0.0020.67913<0.01
TD530.003  ±  0.0030.8047<0.02
TD900.005  ±  0.0060.5868NS
TD90.005  ±  0.0040.46811NS
TD160.003  ±  0.0040.24112NS
TD500.001  ±  0.0010.49410NS
TD600.001  ±  0.0020.5089NS
TD1−0.001  ±  0.0050.4015NS
TD6−0.002  ±  0.0040.3448NS
TD7−0.005  ±  0.0040.64112<0.05
TD5−0.007  ±  0.0040.80010<0.01
  • Selection coefficients (s) were measured as in Fig. 1. Strains are arranged in descending order of the estimated selection coefficient. The final three columns report the correlation coefficient (R), the number of time points at which genotype frequencies were measured (n), and the statistical significance (P) for a test of the null hypothesis that the slope is not different from zero. NS, not significant.

  • * Produces small colonies on rich medium, fails to grow with glycerol as primary carbon source (petite).

  • Produces small colonies on rich medium, marginal growth with glycerol as primary carbon source.

  • Produces small colonies on minimal medium.