Table 1

Histological scores for AIA in IL-6-deficient and wild-type mice

GroupGenotypeMice per groupHistology score of mice at day 35
01234Mean ± SE
I IL-6 +/+10283.8 ± 0.18 
IIIL-6 −/−10281.8 ± 0.18*
  • Both groups were immunized in the standard manner and sacrificed 35 days after the first immunization. The histopathologies of the knee joints were scored from 0 to 4 as described in Materials and Methods. ∗, P < 0.001, IL-6 −/− compared to IL-6 +/+.