Table 1

DSB-promoted recombination by popout recombination and gene conversion

Transfected DNAFrequency neo+ coloniesFrequency neo+hyg+ colonies
pCMV3xnlsI-SceI4.0  ×  10−3 0.9  ×  10−3
pCMV-lacZ ≤2  ×  10−5 ≤2  ×  10−5