Table 1

Serum and tissue iron values in aceruloplasminemic mice

MiceHb, g/dlSerum iron, μg/dlTIBC, μg/dlTransferrin saturation, %Ferritin, ng/mlIron content, μg/g dry wt
LiverSpleen
Cp +/+ 14.1  ± 3.3252  ± 25477  ± 4543  ± 7112  ± 10252  ± 64224  ± 63
Cp −/− 13.9  ± 3.4245  ± 100517  ± 3033  ± 5410  ± 103*666  ± 130*1,294  ± 94*
  • Values are means ± standard deviations, n = 3 from each group at 1 year of age. Hb, hemoglobin; (Hb), TIBC, total iron binding capacity. Significant differences were observed between Cp+/+ and Cp−/− mice for serum ferritin, (∗, P < 0.001), liver tissue iron content, (∗, P < 0.001), and spleen tissue iron content (∗, P < 0.001 in all cases).