Table 3

Correlation between virulence factor genotypes and disease prevalence

GeneTotal, n = 114 (%)Gastric adenocarcinoma, n = 27 (%)Duodenal ulcer, n = 23 (%)MALT, n = 29 (%)Gastritis, n = 35 (%)P value gastric adenocarcinoma vs. antral gastritisP value duodenal ulcer vs. antral gastritis
vacAs1 99  (86.8)26  (96.3)23  (100)21  (72.4)29  (82.9)0.1260.036
vacAs2 15  (13.2)1  (3.7)0  (0)8  (27.6)6  (17.1)n.s.n.s.
vacAm1 54  (47.4)20  (74.1)8  (34.7)10  (34.5)16  (45.7)0.025n.s.
vacAm2 60  (52.6)7  (25.9)15  (65.2)19  (65.5)19  (54.3)n.s.n.s.
cagA 89  (78.9)25  (92.6)23  (100)14  (48.3)27  (77.1)0.0940.008
babA2 82  (71.9)21  (77.8)23  (100)20  (69.0)18  (51.4)0.0330.0002
Type 184  (73.7)23  (85.1)23  (100)12  (41.4)25  (71.4)0.2350.0041
Triple-positive68  (59.6)20  (74.1)23  (100)20  (34.5)15  (42.9)0.0142 × 10−6
  • The P value of gastric adencarcinoma vs. antral gastritis was calculated with the χ2 test. The P value of duodenal ulcer vs. antral gastritis was calculated with Fisher’s exact two-sided P test. n.s., not significant.