Table 1

Number of ALL cases and controls, adjusted ORs and 95% CIs by MTHFR 677, using 677CC as a reference, and MTHFR1298, using 1298AA as a reference

VariableCaseControlOR*95% CI
MTHFR 677
 CC35  (50.7)61  (53.5)1
 CT29  (42.0)39  (34.2)0.58(0.27, 1.28)
 TT 5  (7.2)14  (12.3)0.23(0.06, 0.81)
 SNA 2 0
MTHFR 1298§
 AA45  (65.2)49  (43.0)1
 AC23  (33.3)54  (47.4)0.33(0.15, 0.73)
 CC 1  (1.5)11  (9.6)0.07(0.00, 1.77)
 SNA 2 0
  • * OR was estimated by using conditional logistic regression adjusting for other polymorphism. 

  • MTHFR 677CC as reference. 

  • Sample not available or did not amplify. 

  • § MTHFR 1298AA as reference. 

  • OR and 95% CI computed by using exact methods with adjustment for sex, age, and the other polymorphism.