Table 3

Number of AML cases and controls, adjusted ORs and 95% CIs by MTHFR 677, using 677CC as a reference, and MTHFR 1298, using 1298AA as a reference

VariableCaseControlOR*95% CI
MTHFR 677
 CC134  (60.1)196  (53.1)1
 CT 66  (29.6)130  (35.2)0.73(0.48, 1.11)
 TT 23  (10.3) 43  (11.7)0.84(0.43, 1.62)
 SNA 14 8
MTHFR 1298§
 AA 99  (45.0)165  (45.6)1
 AC 98  (44.5)157  (43.4)0.99(0.66, 1.50)
 CC 23  (10.5) 40  (11.0)0.95(0.51, 1.76)
 SNA1715
  • * OR was estimated by using conditional logistic regression adjusting for other polymorphism. 

  • MTHFR 677CC as reference. 

  • Sample not available or did not amplify. 

  • § MTHFR 1298AA as reference.