Table 3

Estimates of the decline in mean viability per generation among nonlethal lines (ΔM), mutational variance for viability (ΔV), rate of mutations affecting viability per haploid second chromosome per generation under an equal-effects model (UBM), and effect of the mutations (SBM)

Data setΔM, %ΔV × 104UBMSBM
25°C, G27 + G330.24  (0.16–0.31)2.7  (1.6–3.6)0.021  (0.011–0.038)0.113  (0.073–0.162)
25°C, G270.24  (0.13–0.34)1.9  (0.80–3.0)0.029  (0.012–0.066)0.081  (0.040–0.134)
25°C, G330.23  (0.12–0.35)3.4  (1.8–4.9)0.016  (0.0051–0.036)0.147  (0.081–0.262)
Mukai 1964 (7)0.381.0 0.140.027
Mukai et al. 1972 (8)0.400.940.170.023
Ohnishi 1977 (9)0.170.510.060.030
  • Bootstrap 95% confidence intervals are given in parentheses. 25°C estimates are based on data pooled across treatments. Estimates from the other studies are those based on excluding “severely deleterious” lines (usually, those with viability <50% of the controls); this is the most relevant comparison, because there were no lines with <65% viability of the controls at 25°C (Fig. 2).