Table 1

Patient characteristics

PatientAge, monthsSexWBC, × 103/μlHSMImmunophenotypeKaryotypeMLL-AF4 fusion transcript
INF-12F6B46,XX,t(4;11)(q21;q23)[12]/46,XX[8]+
INF-24F346+B46,XX,t(4;11)(q21;q23)[10]+
INF-33F285+BNot determined+
INF-41F410+BNot determined+
INF-58M1,000+B46,XY,t(4;11)(q21;q23),t(14;19)(q11.2;p13)[12]/46,XY[8]+
INF-62F670+B46,XX,t(4;11)(q21;q23)[20]+
INF-73F684+B46,XX,t(4;11)(q21;q23)[17]/46,XX[3]+
INF-89F41+B46,XX[29]+
INF-92M187+B46,XY,t(4;11)(q21;q23)[16]/46,XY[6]+
INF-105M317+BNot determined+
INF-112M270+B46,XX,t(11;19)(q23;p13)[20]
INF-126M83BNot determined
  • MLL-AF4 fusion transcript expression was determined by RT-PCR. HSM, hepatosplenomegaly; WBC, white blood cells; INF, infant; M, male; F, female; B, B-lineage.