Table 1

Parameters estimation from both Finland and Iceland data

ParameterSymbolFinlandIcelandComments
Reproductive number R 0 2.0 (1.9–5.8)2.1
Duration of carriage1/f1.1 (0.8–5.3)2.6 (0.9–2.9)Months
Maximum age1/μ7284Months
Superinfection fitnessφ0.43 (0.20–0.8)1 (0.44–1)ℛ → 𝒮
Transmission fitnessR0′/R01.29 (1.20–1.8)1.44 (1.28–1.56)
Initial resistancelog10 𝒵0−2.7 (−5.0–−2.3)−3.1 (−3.8–−2.7)
Treatment rateγ1.42 (0.8–3.5)1.43Courses/year
Change in consumptionρ50.9%−12.7%
Treatment duration1/g1010Days
Mutation probabilityσ00Not used
Antibiotic consumption (of children)a ≃ γ/g37.7 (4%)38.0 (4%)Infant DDDs/1,000 children
Period of study1978–931988–96
χ2 (df)16.08 (10)11.134 (5)
Goodness-of-fit P value P 0.110.06
  • Fitted parameters are shown with 95% confidence intervals.