Table 1

Summary of unitary mechanical parameters

Myosin typed, nmton, msF, pNton, ms
Smooth 2HD9.2  ±  0.5 (14)167  ±  23 (14)1.5  ±  0.1 (6)284  ±  54 (5)
Smooth 1HD5.7  ±  0.3* (18)150  ±  19 (14)0.6  ±  0.1* (9)263  ±  49 (8)
Skeletal 2HD11.6  ±  0.7 (10)48  ±  2 (2)1.3  ±  0.1 (11)166  ±  25 (7)
Skeletal 1HD6.8  ±  0.6* (14)44  ±  7 (11)0.8  ±  0.1* (20)149  ±  52 (6)
  • Data are presented as the mean ± SEM. The quantities in parentheses represent the number of MV histograms contributing to the mean. 1HD, single-headed; 2HD, double-headed. 

  • * P < 0.05 vs. 2HD. 

  • Unloaded ton for displacement data collected at 10 μM ATP. 

  • Loaded ton for force data collected at 10 μM for smooth-muscle myosin and 1 μM ATP for skeletal-muscle myosin.