Table 1

Genotype of weanling mice and embryos

Developmental stageBkgdBlmh genotype distribution nX*P
+/+ +/− −/−
EOEOEO
WeanlingsB6,12914817529531114810459010.40.0056
1297097140147703527916.20.0003
EmbryosB6,12985151887301.85NS
  • Bkgd, genetic background; E, expected (assuming a 1:2:1 Mendelian distribution) number of mice; O, observed number of mice; NS, not significant. 

  • * χ2 satistic. 

  • Significant at a confidence interval of 0.95.