Table 1

mtDNA rearrangement breakpoints in Ant1tm2Mgr (−/−) hearts

mtDNA size5′ breakpointDeleted region3′ breakpoint
16,11813,936
1.8 kb TAATGCCAAACCC AAAAAAACAC … AAACCCTAAA ACCATTAAACAA
15,92813,099
2.5 kb TTATTTTGGCCTA CTTTCATCAA … ACCCAATCAA ACGCCTAGCATT
16,10112,533
3.2 kb CCCCCACCCCCTC CTCTTAATGC … CCACCCCCTC ACGACTAATAAT
  • Nucleotide numbers coincide with the published mouse mtDNA sequence (31). Direct repeats are underlined.