Table 1

Characteristics of experimental animals and numbers of BrdUrd-labeled cells in the dentate gyrus

No.SpeciesAgeSexNo. of BrdUrd injectionsSurvival timeNo. of BrdUrdlabeled cells
1 M. fascicularis  5 (YA)M52 weeks4,308
2 M. fascicularis  5 (YA)M12 hr3,288
3 M. fascicularis  7 (MA)F52 weeks1,968
4 M. fascicularis 10 (MA)M31 week2,748
5 M. mulatta 10 (MA)F52 weeks1,896
6 M. mulatta 12 (MA)F52 weeks1,176
7 M. fascicularis 15 (MA)F32 weeks780
8 M. fascicularis 16 (MA)M12 hr876
9 M. fascicularis 23 (A)M12 hr420
10 M. fascicularis 23 (A)M12 hr336
11 M. fascicularis 23 (A)M12 hr228
  • Animals were injected with 75 mg/kg BrdUrd i.p. 1–5 times. Multiple injections were separated by 24 hr. Survival time represents time after the last BrdUrd injection when the monkey was perfused. YA, young adult; MA, middle-aged adult; A, aged adult (15, 16).