Table 2

Relationship between KvDMR1 methylation and imprinting in HCC samples

GeneRatio*HCCKvDMR1 methylationFisher exact test probability
P = MP > M
SLC22A1L Abnormal220.51
CDKN1C Abnormal060.035
IGF2 Abnormal140.039
  • * Abnormal ratio indicates the detection of GOI, LOI or INV. Normal ratio indicates the presence of the same allelic expression pattern in normal and matched HCC. 

  • P, paternal pattern of methylation; M, maternal pattern of methylation. 

  • Probability <0.05 is statistically significant.