Table 3

Spermatogenic potential of cryptorchid α6hi SSClo testis cells after FACS separation by c-kit expression

Fraction*Testes colonizedColonies/testisFold§ (colony)Area/testis, mm2Fold§ (area)
Cryptorchid11 /1118  ± 419.4  ± 2.71
I (c-kit)11 /12118  ± 226.654  ± 105.7
II (c-kitlo)11 /1288  ± 204.939  ± 84.1
III (c-kit+)2 /111.8  ± 1.20.10.5  ± 0.40.05
  • * Unsorted cryptorchid testes from mice 14–20 wks of age were used as control. Fractions (I–III) from Fig. 3A

  • Number of testes colonized/number of testes analyzed. 

  • Reported as described in Table 1 (mean ± SEM). 

  • § Fold enrichment compared to cryptorchid control (calculated as described in Table 1).