Table 3

Kinetic rate constants at 37°C by surface plasmon resonance

ka, M−1⋅s−1kd, s−1KD, nM
BH10 full-length gp1206.72 × 104  ± 1 × 1021.5 × 10−3  ± 4 × 10−422  ± 6
Core gp1206.27 × 104  ± 9 × 1021.4 × 10−2  ± 2 × 10−3220  ± 40