Table 1

Lethality of the P. aeruginosa ppk mutant in a burned-mouse model

StrainRelevant genotypeMortality, mice dead/total*
Exp. 1Exp. 2Exp. 3Average, %
PAO1WT7/75/66/694
PAOM5Δppk∷TcR1/50/50/57
PAOM5 (pHEPAK11)Δppk∷TcR (PPK+++)2/53/53/553
  • * Burned-mice were inoculated s.c. with ≈200 cells of each strain; mortality was checked after 48 h. Exp., experiment.