Table 5

Serum lipid profile of ArKO and WT mice

MiceLipid, mmol/liter
CholesterolTriglyceridesHDL
Females
 3–4 months
  ArKO3.63  ± 0.41 (6)1.40  ± 0.22 (6)2.28  ± 0.26 (6)
  WT3.25  ± 0.15 (12)1.27  ± 0.11 (12)2.20  ± 0.12 (12)
 1 year
  ArKO4.34  ± 0.63 (5)*2.28  ± 0.57 (5)2.92  ± 0.33 (5)*
  WT2.74  ± 0.28 (5)2.23  ± 0.49 (5)1.77  ± 0.18 (5)
Males
 3–4 months
  ArKO4.29  ± 0.22 (16)2.85  ± 0.35 (16)1.57  ± 0.10 (16)
  WT4.08  ± 0.25 (23)2.38  ± 0.22 (23)1.75  ± 0.19 (23)
 1 year
  ArKO4.79  ± 0.73 (7)*3.27  ± 0.39 (7)*2.84  ± 0.33 (7)*
  WT3.39  ± 0.29 (8)2.08  ± 0.43 (8)2.10  ± 0.26 (8)
  • Results are presented as mean ± SEM (n). *, At least P < 0.05 compared to WT.