Table 1

Prospective follow-up of NOD mice for insulin autoantibodies with the microassay and onset of diabetes

Age of developing IAA, weeksAge of diabetes onset, weeks
 8 (n = 6)16, 16, 16, 16, 18, 26*
12 (n = 1)20
16 (n = 3)16, 24, 24
20 (n = 2)24, 26
24 (n = 1)>36
Negative (n = 2)24, >36
  • * This mouse showed a diabetic blood glucose level at 16 weeks of age (251 mg/dl), which reverted to normal for 10 weeks (see Fig. 5).