Table 1

Plasma lipid, glucose, and insulin levels in lean (+/+) and obese (fa/fa) ZDF rats

RatsAge, wknSubstances measured
FFA, mMTG, mMGlucose, mMInsulin, microunits/ml
Lean wild type (+/+)730.33  ± 0.070.87  ± 0.124.97  ± 0.167.8  ±  1.5
1430.59  ± 0.310.99  ± 0.245.24  ± 0.227.6  ±  0.8
2030.61  ± 0.230.84  ± 0.085.54  ± 0.188.2  ±  1.2
Obese ZDF (fa/fa)731.35  ± 0.371.1   ± 0.334.36  ± 0.235.6  ±  3.5
1462.02  ± 0.44*6.27  ± 1.57*12.22  ± 2.22*121   ± 11.2*
2032.24  ± 0.588.98  ± 2.8111.54  ± 2.7759.5  ±  3
TGZ-treated (fa/fa)1461.28  ± 0.411.59  ± 0.175.11  ± 0.0831.7  ±  3.4
  • *P < 0.05, untreated obese (fa/fa) rats vs. lean (+/+) rats. 

  • P < 0.05, 14-wk-old TGZ-treated obese (fa/fa) rats vs. untreated 14-wk-old obese (fa/fa) rats.