Table 2

Effect of leptin replacement on numbers of circulating leukocytes and erythrocytes

ob/obLeptin-replaced ob/ob+/?
RBC (106/μl)10.80  ±  0.2210.18  ±  0.4310.28  ±  0.23
WBC (103/μl)4.87  ±  0.368.72  ±  0.07**7.15  ±  1.14*
Lymphocytes/μl3720.75  ±  55.407941.25  ±  146.43**6829.25  ±  854.91**
Monocytes/μl284.50  ±  64.6556.25  ±  18.05**67.75  ±  19.62**
Neutrophils/μl843.75  ±  270.02522.50  ±  59.05400.25  ±  125.52
  • ob/ob mice received two daily injections of either saline (ob/ob) or leptin (leptin-replaced ob/ob). +/? mice were left untreated. Data are mean ± SEM of four mice per group. *, P < 0.05; **, P < 0.01 vs. ob/ob mice by factorial ANOVA.