Table 1

Steroid studies: Blood values at M0, M6, and M12

GroupnDHEAS, μmol/liter Testo, nmol/liter ADG, nmol/liter E2, pmol/liter
M0M6M12M0M6M12M0M6M12M0M6M12
Men <70
 DHEA362.90  ± 0.1910.4  ± 0.92**††7.22  ± 0.65**††18.4  ± 1.120.9  ± 1.1118.1  ± 0.9114.3  ± 1.0329.0  ± 2.42**23.4  ± 2.98**71  ± 2.778  ± 3.281  ± 2.4*
 Placebo312.65  ± 0.161.81  ± 0.192.66  ± 0.1920.0  ± 1.1518.7  ± 1.098.2  ± 0.9615.2  ± 1.5015.6  ± 1.6716.2  ± 1.7673  ± 3.873  ± 4.076  ± 3.7
Men >70
 DHEA302.44  ± 0.2210.3  ± 1.06**††8.98  ± 0.87**††19.3  ± 1.1220.6  ± 0.9620.7  ± 1.1713.7  ± 1.2833.5  ± 3.06**35.3  ± 3.61**74  ± 3.476  ± 3.481  ± 4.4*
 Placebo362.14  ± 0.131.44  ± 0.162.00  ± 0.1919.3  ± 1.4820.1  ± 1.7618.6  ± 1.8114.0  ± 1.2915.9  ± 1.8815.1  ± 1.4874  ± 3.079  ± 3.380  ± 3.4
Women  <70
 DHEA352.01  ± 0.168.03  ± 0.71**††5.24  ± 0.43**1.30  ± 0.12.3  ± 0.1*1.60  ± 0.14.5  ± 0.529.5  ± 3.6**††20.5  ± 2.5**††28  ± 1.839  ± 1.6**37  ± 1.6**
 Placebo352.19  ± 0.191.54  ± 0.162.11  ± 0.241.16  ± 0.081.3  ± 0.091.23  ± 0.083.9  ± 0.433.90  ± 0.364.2  ± 0.4227  ± 1.329  ± 1.627  ± 1.9
Women  >70
 DHEA311.66  ± 0.119.77  ± 1.09**††7.19  ± 0.57**††1.09  ± 0.092.35  ± 0.15*1.92  ± 0.13*3.3  ± 0.327.8  ± 2.0**††26.4  ± 2.5**††25  ± 1.237  ± 1.8**35  ± 2.0**
 Placebo341.81  ± 0.191.19  ± 0.131.57  ± 0.191.17  ± 0.111.31  ± 0.141.25  ± 0.123.8  ± 0.423.90  ± 0.473.90  ± 0.3926  ± 1.426  ± 1.0427  ± 1.7
  • *, P < 0.05; **, P < 0.01 vs. M0 of the same group. †, P < 0.05; ††, P < 0.01 vs. placebo group of same age and gender.