Table 1

Comparison of migration speed and directional persistence of FAK-null and FAK-expressing cells

Speed, μm/minPersistence, min
FAK-null0.364  ± 0.175 (n = 14)13.668  ± 8.145 (n = 14)
WT-FAK0.827  ± 0.345 (n = 18)20.039  ± 10.87 (n = 18)
F397-FAK0.585  ± 0.222 (n = 15)10.002  ± 4.959 (n = 15)
  • Values are means ± SD. Migration speed and directional persistence of FAK-null and F397 cells were both significantly smaller than those of FAK-expressing cells (P = 0.0003 and 0.033 for speed, P = 0.0186 and 0.0087 for persistence, respectively).