Table 1

Absolute and relative expression values for genes discussed in text

Function*/ gene identityIdentity/homology§Highest absolute value (SD)**/relative value‡‡
NaiveE. coliM. luteusB. bassiana
Caspase
 CG7486 (Dredd) Death related ced-3/Nedd2-like protein 0.42 (0.17)0.72/1.70.74/1.80.46 (0.08)/1.1
 CG7788 (Ice) Interleukin-1 beta-converting enzyme 0.44 (0.27)1.07 (0.52)/2.50.92 (0.49)/2.11.35 (0.25)/3.1
 CG14902 (Decay) Death executioner caspase related to Apopain 0.65 (0.19)0.59 (0.16)/0.90.66 (0.02)/1.01.22 (0.44)/1.9
 CG18188 (Daydream) Death Associated Molecule related to Mch2 0.32 (0.08)0.42 (0.15)/1.30.79 (0.25)/2.50.61 (0.07)/1.9
Defense or immunity protein
 CG11709 (PGRP-SA) Peptidoglycan recognition protein-SA 1.09 (0.40)3.9 (1.4)/3.63.9 (1.7)/3.62.82 (0.85)/2.6
 CG9681 (PGRP-SB1) Peptidoglycan recognition protein-SB1 6.2 (2.6)28.6 (9.0)/4.620.3 (7.7)/3.25.2 (3.0)/0.8
 CG14745 (PGRP-SC2) Peptidoglycan recognition protein-SC2 3.5 (1.7)22.0 (7.1)/6.316.4 (6.2)/4.77.7 (2.0)/2.2
 CG7496 (PGRP-SD) Peptidoglycan recognition protein-SD 0.49 (0.21)3.0 (1.3)/6.12.38 (0.94)/4.90.97 (0.25)/2.0
 CG14704 (PGRP-LB) Peptidoglycan recognition protein-LB 1.58 (0.55)4.2 (1.5)/2.74.1 (1.8)/2.61.47 (0.40)/0.9
 CG10146 (AttA) Attacin-A 5.7 (2.1)61 (14)/10.866 (10)/11.716.8 (4.1)/2.9
 CG18372 (AttB) Attacin-B 13.9 (5.8)79 (21)/5.782 (17)/5.923.5 (5.3)/1.7
 CG4740 (AttC) Attacin-C 7.3 (3.3)52 (16)/7.147 (15)/6.48.6 (2.5)/1.2
 CG7629 (AttD) Attacin-D 0.32 (0.16)9.5 (4.6)/29.55.3 (3.5)/16.40.41 (0.08)/1.3
 CG1365 (CecA1) Cecropin A1 10.7 (4.7)73 (27)/6.877 (23)/7.213.6 (3.0)/1.3
 CG1367 (CecA2) Cecropin A2 4.8 (2.2)63 (15)/13.169.5 (12.9)/14.48.5 (2.2)/1.8
 CG1878 (CecB) Cecropin B A1.7 (0.9)/ 3.2 (1.6)/ ††/ 
 CG1373 (CecC) Cecropin C 0.45 (0.16)9.9 (3.0)/22.011.1 (5.2)/24.70.61 (0.10)/1.4
 CG12763 (Dpt) Diptericin A 19.8 (7.7)70 (37)/3.553 (12)/2.715.3 (3.7)/0.8
 CG10794 (DptB) Diptericin B 12.7 (5.6)63 (32)/5.056 (13)/4.413.1 (3.4)/1.0
 CG1385 (Def) Defensin 4.3 (2.2)26.5 (7.9)/6.218.2 (8.0)/4.33.76 (0.87)/0.9
 CG10816 (Dro) Drosocin 14.1 (6.6)53.5 (14.7)/3.847 (12)/3.320.1 (3.9)/1.4
 CG10810 (Drs) Drosomycin 18.5 (7.4)49 (16)/2.658 (21)/3.151 (23)/2.8
 CG8175 (Mtk) Metchnikowin 30 (12)85 (33)/2.976 (32)/2.554 (17)/1.8
 CG12780Gram-negative binding protein1.93 (0.93)3.1 (1.6)/1.63.6 (1.3)/1.94.3 (1.6)/2.2
 CG13422Gram-negative binding protein2.4 (1.2)25.5 (7.0)/10.630.5 (5.4)/12.723.5 (3.9)/9.8
 CG7052 (TepII) Thiolesther containing protein II 0.31 (0.017)2.19 (0.90)/7.12.3 (1.7)/7.62.51 (0.70)/8.2
 CG1361 (Anp) Andropin 48 (14)50.0 (8.1)/1.058 (10)/1.240 (12)/0.8
Endopeptidase
 CG10882Kallikrein0.350.72 (0.24)/2.00.75 (0.17)/2.10.46 (0.10)/1.3
 CG16821Kallikrein0.180.29/1.60.39 (0.27)/2.20.19 (0.03)/1.1
 CG4920 (ea) Easter 0.52 (0.10)0.63/1.20.60 (0.07)/1.20.65/1.2
 CG2045Easter serine protease2.17 (0.76)2.72 (0.74)/1.26.1 (1.8)/2.86.8 (1.7)/3.1
 CG3505Easter serine protease1.24 (0.44)2.6 (1.1)/2.02.63 (0.84)/2.12.92 (0.66)/2.4
 CG16705Easter serine protease4.7 (1.7)5.4 (1.9)/1.212.1 (6.6)/2.618.6 (3.4)/4.0
 CG7996 (snk) Snake 0.59 (0.14)0.70 (0.01)/1.20.78 (0.13)/1.30.38 (0.14)/0.6
 CG11841Snake—coagulation factor XI4.6 (1.6)3.28 (0.98)/0.75.9 (2.8)/1.310.0 (3.2)/2.2
 CG11842Snake—trypsin-like serine protease0.94 (0.24)1.53 (0.71)/1.62.7 (1.1)/2.93.06 (0.80)/3.3
 CG11843Snake—trypsin-like serine protease0.260.42 (0.11)/1.60.49 (0.44)/1.80.68 (0.20)/2.6
 CG9645Stubble stubbloide—transmembrane domain2.06 (0.91)2.9 (1.1)/1.46.9 (2.3)/3.44.9 (1.1)/2.4
 CG9372Stubble—hemocyte protease-I1.50 (0.51)1.32 (0.38)/0.92.35 (0.85)/1.63.09 (0.99)/2.1
 CG2105Corin “transmembrane mosaic serine protease”0.21 (0.59)0.51 (0.02)/2.50.74/3.60.59 (0.11)/2.9
 CG11459Cathepsin L0.74 (0.12)1.42 (0.54)/1.91.86 (0.79)/2.53.6 (1.8)/4.9
 CG11836Hepsin—coagulation factor X precursor0.180.37 (0.09)/2.10.37/2.10.15/0.9
 CG6639Masquerade0.290.50 (0.03)/1.710.7 (8.0)/36.417.8 (4.4)/60.5
Growth factor
 CG9224 (sog) Short gastrulation 0.30.45 (0.13)/1.50.62 (0.16)/2.10.29 (0.13)/1.0
 CG4559 (Idgf3) Imaginal Disc Growth Factor 3 4.8 (1.7)10.3 (4.5)/2.210.5 (4.0)/2.27.6 (2.4)/1.6
 CG9885 (dpp) Decapentaplegic 0.130.32/2.4 / 
Motor protein
 CG16910 (key) Kenny 0.61 (0.20)0.80 (0.39)/1.30.78 (0.33)/1.30.74 (0.15)/1.2
Serpins
 CG6687Necrotic-like—squamous cell carcinoma antigen 13.0 (1.3)8.1 (3.1)/2.714.9 (9.0)/5.022.2 (4.1)/7.4
 CG1857 (nec) Necrotic 3.3 (1.4)7.2 (2.9)/2.215.4 (5.8)/4.616.2 (4.9)/4.9
 CG9453 (sp1) Serpin 1 1.65 (0.63)1.95 (0.74)/1.21.76 (0.65)/1.12.14 (0.55)/1.3
 CG8137 (sp2) Serpin 2 1.15 (0.50)1.76 (0.57)/1.52.0 (1.1)/1.80.95 (0.30)/0.8
 CG9334 (sp3) Serpin 3 4.0 (1.9)5.5 (1.5)/1.45.4 (2.5)/1.43.3 (1.1)/0.8
 CG9456 (sp4) Serpin 4 2.21 (0.97)2.8 (1.0)/1.34.2 (1.4)/1.95.4 (1.3)/2.4
 CG18525 (sp5) Serpin 5 0.96 (0.33)2.27 (0.78)/2.43.0 (1.2)/3.12.04 (0.39)/2.1
 CG10913 (sp6)Serpin 6 (not on Affymetrix microarray)
Signal transduction protein
 CG5576 (Imd—BG5) Death Domain 0.230.35/1.50.38/1.6 / 
Specific RNA polymerase II transcriptional factor
 CG6667 (dl) Dorsal 0.110.75 (0.33)/6.61.00 (0.36)/8.80.30 (0.19)/2.6
 CG11992 (Rel) Relish 0.86 (0.42)2.8 (1.4)/3.33.0 (1.3)/3.52.79 (0.71)/3.3
 CG6794 (Dif) Dorsal-related immunity factor 0.36 (0.02)0.37/1.00.25/0.70.26 (0.004)/0.7
Transcription factor associated
 CG5848 (cact) Cactus 1.48 (0.69)2.2 (1.1)/1.54.5 (1.4)/3.14.0 (1.2)/2.7
  • Absolute and relative levels of expression for Drosophila genes discussed within the text, following challenge the Gram-negative E. coli, the Gram-positive M. luteus, or the fungus B. bassiana, where function or gene identity was given in Flybase on or before June 1, 2001. 

  • * Functional categories of genes imposed by FlyBase. 

  • Gene identifier or CG number applied to each gene following from complete sequencing of the Drosophila genome by Celera. 

  • Fully identified genes are indicated in bold type and the associated gene acronyms are indicated in brackets after the CG number. 

  • § Genes with homology and/or proposed function, but no clear identity, are indicated in ordinary type. 

  • Absolute level of gene expression in naive flies was less than 0.01; therefore, no relative values were calculated. 

  • The absolute values are the maximum levels of induction observed, regardless of when this occurred during the time course. 

  • ** SD for highest absolute value. 

  • ‡‡ The relative values given are the maximum absolute level of induction as a ratio of the absolute expression level seen in naive animals. Where relative gene induction exceeds the 2-fold or more threshold, the relative values are indicated in bold. 

  • †† No data for a particular gene/treatment combination.