Table 1

Quantification of in vivo endothelial cell apoptosis in retinas of mice with ischemic retinopathy

Treatmentn% Apoptotic endothelial cells*
PBS43.3  ± 0.4
PEDF (11.2 μg/day)426.7  ± 1.5
  • * Proportion of TUNEL positive endothelial cells in the retina in one representative sagittal section. Range of total endothelial cells in PBS group was 155–268 and in PEDF group was 78–94. 

  • P < 0.000005.