Table 1

Identities of the 22 genes displaying strong circadian oscillations in control flies in both LD 12:12 and DD

GeneA0Phase LD (ZT)Phase DD (CT)Expression mean (min:max)Function
tim 0.961283,374.9 (876.6:8,390.2)Circadian rhythm
per 0.94168957.7 (97.9:2,531.9)Circadian rhythm
vri 0.841283,350.5 (1,564.5:7,146.2)Circadian rhythm; RNA polymerase II transcription factor
Clk 0.922020477.2 (44.2:1,098.7)Circadian rhythm
Dreg-2 0.86441,573.4 (1,112.0:2,107.6)Haloacid dehalogenase/epoxide hydrolase family
puc 0.941241,845.6 (1,157.9:2,814.9)JUN kinase phosphatase
Ugt35b 0.9005,342.6 (2,615.3:8,887.5)UDP-glucuronosyltransferase
Cyp4d21 0.9120162,081.3 (969.8:4,728.8)Cytochrome P450
Amp 0.772003,323.5 (2,134.5:5,517.0)Synaptic vesicle endocytosis
Pdh 0.9802018,375.0 (5,817.3:32,515.9)Oxidoreductase, acting on the CH-OH group of donors, NAD or NADP as acceptor
Slob 0.991686,260.6 (3,054.3:9,768.0)Potassium channel-binding protein; signal transduction
CG57980.941282,732.0 (958.2:6,526.6)Ubiquitin-specific protease
CG71490.920161,949.5 (1,221.4:3,395.0)Diacylglycerol cholinephosphotransferase
CG100910.88841,895.7 (930.5:3,467.3)Glutathione transferase
CG102370.820166,465.7 (3,994.5:12,993.8)α-Tocopherol transfer protein-like; retinaldehyde binding
CG114070.9120203,058.6 (1,661.2:6,640.5)Long-chain fatty acid transporter
CG117960.83448,371.2 (4,750.0:11,891.0)4-Hydroxyphenylpyruvate dioxygenase
CG173860.982016533.3 (−47.1:2,319.8)RNA binding
CG94970.90162,642.4 (949.3:5,657.0)Unknown
CG49620.8912162,355.6 (431.1:4,998.2)Unknown
CG105530.850161,725.0 (824.9:3,937.9)Unknown
CG118910.860161,425.9 (351.1:3,682.3)Unknown
  • “Phase LD” and “Phase DD” refer to collection times of peak expression. ZT, Zeitgeber time; CT, circadian time. “Expression” lists mean, peak, and trough expression levels across the three LD cycles in microarray fluorescence units. Functional annotations based on Affymetrix annotations and the Gene Ontology database (36).