Table 1.

The effective kinetic parameters for the SOS system (±SD)

GenekβEFunction
uvrA 0.09  ± 0.042,800  ± 3000.14Nucleotide excision repair
lexA 0.15  ± 0.082,200  ± 1000.10Transcriptional repressor
recA 0.16  ± 0.073,300  ± 2000.12Mediates LexA autocleavage, blocks replication forks
umuD 0.19  ± 0.1330  ± 300.21Mutagenesis repair
polB 0.35  ± 0.1570  ± 100.31Trans-lesion DNA synthesis, replication fork recovery
ruvA 0.37  ± 0.130  ± 20.22Double-strand break repair
uvrD 0.65  ± 0.3170  ± 200.20Nucleotide excision repair, recombinational repair
uvrY 0.51  ± 0.25300  ± 2000.45SOS operon of unknown function, additional roles in two-component signaling
lacZ 1.53Unrelated to SOS system
  • E is the mean error for the promoter activity prediction (see Methods).