Table 1.

Body weight, VO2, and respiratory exchange ratio in response to TNP-470

Mice Time, day Body weight, gVO2, ml/kg/minRespiratory exchange ratio
SalineTNPSalineTNPSalineTNP
C57BL6023.0  ± 0.522.6  ± 0.2
422.8  ± 0.421.8  ± 0.444.4  ± 0.842.5  ± 3.20.70  ± 0.020.69  ± 0.01
823.0  ± 0.421.1  ± 0.331.9  ± 0.838.3  ± 1.10.71  ± 0.030.67  ± 0.03
ob/ob041.4  ± 0.741.7  ± 0.7
443.9  ± 0.641.1  ± 0.924.3  ± 1.130.0  ± 2.00.74  ± 0.110.70  ± 0.01
846.2  ± 0.536.7  ± 1.119.1  ± 0.524.0  ± 0.50.76  ± 0.040.64  ± 0.05
  • * P < 0.05.