Table 5.

Analysis of Apc truncation mutations in intestinal tumors from Mbd4−/−/Apc1638N/+ mice

WT/Apc1638N/+ (%)Mbd4−/−/Apc1638N/+ (%)
Tumors22 (100)29 (100)
 With Apc truncations7 (32)23 (79)
 With >1 mutant allele0 (0)8 (28)
Total Apc mutations7 (100)34 (100)
  • * Combined with data from ref. 20.

  • Compared with Apc1638N/+ mice: P = 0.001; Fisher's exact test.