Table 1.

LH pulse parameters (mean ± SD) in castrated control (WT) and GPR-4 transgenic female and male rats

LH, ng/mlPulse frequency (pulses/2 h)Pulse amplitude, ng/ml
Female WT (n = 6)7.0  ± 1.25.3  ± 0.54.7  ± 0.8
Female GPR-4 (n = 6)1.8  ± 0.71.5  ± 0.64.5  ± 1.4
Male WT (n = 6)5.8  ± 0.94.8  ± 0.53.1  ± 0.5
Male GPR-4 (n = 6)2.1  ± 0.72.5  ± 0.62.7  ± 0.4
  • * Significantly lower than control at P < 0.01 with Mann–Whitney U test.