Table 2

Mast cell localization within murine trachea (mean/10hpf)

SubmucosalIntraepithelial
Sham wild type0.60  ± 0.100
Sham CCR3−/−0.95  ± 0.120.17  ± 0.08
OA wild type0.60  ± 0.060.19  ± 0.05
OA CCR3−/−0.80  ± 0.101.00  ± 0.20*
  • Results shown are expressed as the means ± SEM (sham-treated mice, n = 4; OA-challenged mice, n = 7). The significant difference between OA-challenged wild-type and OA-challenged CCR3−/− mice is indicated as 

  • * , P < 0.002, as determined by unpaired Student's t test.